TB-500 Peptide For Sale — Thymosin Beta-4, Research-Grade
TB-500 (Thymosin Beta-4) is a 43-amino acid peptide fragment studied for systemic tissue repair, wound healing, and anti-inflammatory applications. Independently tested to ≥99% purity via HPLC and Mass Spectrometry. Available in lyophilized powder and nasal spray. Free shipping over $100.
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Research Compound Overview
What Is TB-500? The Systemic Tissue Repair Peptide
TB-500 (Thymosin Beta-4, Tβ4) is a synthetic version of a naturally occurring 43-amino acid peptide found in virtually all human and animal cells. It is derived from the highly conserved C-terminal fragment of Thymosin Beta-4, centered on the actin-binding domain sequence LKKTETQ. Unlike BPC-157, which acts locally, TB-500 is studied for its ability to distribute systemically — making it a unique tool for research into body-wide tissue repair and inflammation modulation.
When you buy TB-500 peptide for sale from PureRawz, every batch is independently verified to ≥99% purity via HPLC and Mass Spectrometry by MZ Biolabs. The Certificate of Analysis for every batch is published publicly on the product page, searchable by lot number.
TB-500 and BPC-157 are the most frequently researched peptide pairing in the recovery and repair research community. Their complementary mechanisms — TB-500’s systemic actin-regulation and BPC-157’s local growth factor modulation — make them the go-to dual-peptide protocol for tissue repair research. PureRawz stocks both at ≥99% purity with independent COA verification.
TB-500 Product Specifications
| Compound Name | TB-500 (Thymosin Beta-4 Fragment, Tβ4) |
| Sequence | Ac-LKKTETQ (active fragment of Tβ4) |
| Amino Acids | 43 (full fragment) |
| Molecular Formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molecular Weight | 4963.5 g/mol |
| CAS Number | 77591-33-4 |
| Purity (PureRawz) | ≥99% HPLC verified |
| Testing Lab | MZ Biolabs (independent, third-party) |
| Storage (lyophilized) | −20°C long-term · 4°C short-term |
| Reconstituted Stability | Up to 28 days refrigerated at 4°C |
| Intended Use | Research purposes only — not for human use |
Available Formats
TB-500 Peptide For Sale in Multiple Research Forms
PureRawz offers TB-500 in two delivery formats. Both forms use the same ≥99% purity compound with batch-specific third-party COA documentation.
Freeze-dried TB-500 in sealed glass vials. Reconstitute with bacteriostatic water. Maximum shelf life — stable 24+ months stored at −20°C. The gold-standard format for subcutaneous peptide research protocols. Available in 5mg, 10mg, 20mg, and bulk 50mg vials for extended programs.
TB-500 in intranasal delivery format using PureRawz’s proprietary suspension technology. Designed for research protocols studying mucosal uptake and systemic distribution via the nasal route. Provides precise, consistent dosing per spray. No reconstitution required.
Peptide Comparison
TB-500 vs BPC-157 — Understanding the Wolverine Stack
TB-500 and BPC-157 are the most frequently compared and co-researched peptides in the repair and recovery research space. Understanding their distinct mechanisms is essential for protocol design.
- Works via actin regulation — promotes cell migration and proliferation
- Distributes systemically throughout the body via lymphatic circulation
- Strong anti-inflammatory properties in animal models
- Promotes angiogenesis — new blood vessel formation
- Studied for cardiac tissue repair, wound healing, and hair follicle activation
- 43-amino acid peptide — larger molecular structure than BPC-157
- Works via growth factor modulation — upregulates GH receptor expression locally
- Acts more locally at the site of administration or injury
- Strong gastrointestinal protective data in animal models
- Promotes tendon-to-bone healing in injury models
- CNS and neuroprotective data in preclinical studies
- 15-amino acid peptide — smaller and more stable structure
Why stack them? TB-500 provides systemic coverage via actin-pathway regulation while BPC-157 delivers targeted local repair via growth factor upregulation. Together, they address tissue repair from two independent mechanisms — which is why the TB-500 + BPC-157 “Wolverine Stack” is the most discussed peptide research combination in 2026. Both compounds are available at PureRawz with ≥99% purity and independent COA verification.
Why PureRawz
Why Researchers Buy TB-500 Peptide From PureRawz
TB-500 is a large peptide with complex synthesis requirements — making purity verification more critical than with simpler compounds. PureRawz holds three non-negotiable standards.
Every TB-500 batch is tested by MZ Biolabs — accredited, independent, third-party. The COA is published publicly on every product page, searchable by lot number. No exceptions, no generic documents shared across batches.
HPLC and Mass Spectrometry confirm purity on every batch. For large peptides like TB-500, impurity profiles matter more than with small molecules. Full impurity documentation is included in every COA.
Manufactured and fulfilled from a US facility. Orders before 2PM EST ship same business day. Domestic delivery in 2–4 business days. Every vial cold-packed where required and shipped in discreet, unmarked packaging.
Preclinical Research Overview
TB-500 Research: What the Preclinical Data Shows
TB-500 has an extensive body of preclinical research spanning multiple tissue types and organ systems. The following summarizes primary research directions. All data reflects animal model findings. TB-500 is not approved for human use.
Primary Research Areas (Animal Models)
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Wound Healing & Skin Repair: TB-500 accelerates wound closure and improves skin repair quality in multiple animal wound models via promotion of keratinocyte and endothelial cell migration through actin regulation.
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Cardiac Tissue Repair: One of the most studied applications — TB-500 has been shown in rodent infarction models to promote cardiac progenitor cell migration and reduce scar tissue formation post-myocardial infarction.
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Tendon & Ligament Healing: Animal models show accelerated tendon repair and improved mechanical properties of healed tissue following TB-500 administration. Frequently studied alongside BPC-157 for comparative and synergistic effects.
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Muscle Repair: Rodent muscle injury models demonstrate TB-500 promotes satellite cell activation and muscle fiber regeneration, with reduced fibrosis compared to controls.
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Angiogenesis: TB-500 promotes new blood vessel formation via VEGF upregulation and endothelial cell migration — a key mechanism underlying its systemic repair profile in ischemia and injury models.
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Anti-Inflammatory Pathways: Animal models show TB-500 reduces inflammatory cytokine levels including IL-1β and TNF-α. This systemic anti-inflammatory activity differentiates it from more locally acting peptides.
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Hair Follicle Activation: In vitro and rodent studies show TB-500 activates hair follicle stem cells and promotes hair growth — an emerging area of dermatological research interest.
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Corneal & Ocular Repair: TB-500 has been studied in corneal wound healing models, showing accelerated epithelial repair and reduced scarring — one of the more clinically advanced application areas with human case data.
TB-500 Legal Status in 2026
TB-500 is legal to purchase in the United States as a research peptide. It is not a controlled substance, not scheduled under the DEA, and does not require a prescription when purchased strictly for laboratory research. The 2026 FDA peptide reclassification discussions have brought increased attention to peptides like TB-500, but it remains fully available as a research compound. PureRawz sells TB-500 in full regulatory compliance — labeled for research use only.
Research Reference
TB-500 Research Dosage Reference — Animal Model Data Only
The following summarizes dosage ranges reported in published preclinical animal research. Provided for reference only. Not a recommendation for human use.
| Research Protocol | Reported Dose (Animal Models) | Route | Duration (Studies) |
|---|---|---|---|
| Wound Healing | 1–6 mg/kg | Subcutaneous / Topical | 7–21 days |
| Cardiac Repair | 2–6 mg/kg | IP or SC injection | Acute – 28 days |
| Tendon / Ligament Repair | 2–4 mg/kg | Subcutaneous | 14–28 days |
| Muscle Regeneration | 2–6 mg/kg | Subcutaneous / IP | 14–42 days |
| Anti-Inflammatory | 1–5 mg/kg | IP or SC injection | Variable |
Data sourced from peer-reviewed preclinical literature. Human equivalent doses, safety, and efficacy are not established. TB-500 is not FDA-approved.
Frequently Asked Questions
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